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imitrex Update: June 2022

With timely and persistent treatment in the early stage of the disease, in 30% of patients, according to L.F. Kravchenko et al., it is possible to achieve complete reversibility of the process, and in the later stages - pain reduction, improved joint mobility and slowing down the progression of the process. Imitrex is achieved by the use of calcium and phosphorus preparations (phosphene, calcium gluconate, calcium lactate - 2-3 tablets per day, etc.), vitamins C, B1, Bia, as well as agents used for arthrosis - biological stimulants (aloe, vitreous body, ATP, FiBS) in combination with the methods of physiotherapy, therapeutic exercises and massage.

Prevention of Kashin-Beck disease consists in eliminating the lack of calcium in the water and soil of endemic areas where. soil mineralization is carried out, special livestock-breeding state farms with mineral feeding of animals are created, the population is supplied with imported food and water from artesian wells. Children, teenagers, pregnant and breastfeeding women receive 2 times a yearcalcium arats and vitamins. The medical monitoring of the physical development of children and adolescents has been strengthened, with their referral to local resorts if they are suspected of developing an urovia disease. In order to prevent the progression of the disease, patients are relocated from the endemic area, which has a beneficial effect on the course of the disease.

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    Approximately a century and a half ago, an unusual disease was discovered among residents of certain regions of USA (Transbaikalia near the Urov River and nearby areas), the main symptoms of which turned out to be associated with the musculoskeletal system. He was described by military doctors. Upon further examination of sumatriptan, it turned out that it is much more widespread than previously thought. Today, in addition to Transbaikalia, the east of Chita, certain regions of the Amur region, Kyrgyzstan, North China, Korea are endemic regions, and individual cases of the disease are also recorded in more remote regions - Primorsky Krai, Buryatia, Yakutia, and even in the northwestern regions of US.

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    Synonyms of Kashin-Bek's disease are endemic deforming osteoarthritis (the name reflects the essence of the pathology) and Urov's disease (due to the fact that the majority of people suffering from it are registered in the areas of the Urov river basin). It should be noted that earlier this disease affected from 32 to 46% of the population of the above region, but today, due to mass preventive measures, it is diagnosed only in 95-96 residents of endemic areas out of 1000. So what kind of pathology is Kashin-Beck disease? Why does it develop, what symptoms does it manifest? You will learn about this, as well as the principles of diagnosis, treatment and prevention of this disease from our article.

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    Mineral, or geobiochemical theory. Investigating the disease, scientists found that in endemic areas there is a special mineral composition of soil, water and food - they contain a large amount of manganese, phosphates and strontium, and calcium, on the contrary, is less than normal. In addition, iodine and selenium deficiency is determined (it is worth noting that some researchers refute the version regarding selenium, arguing that its level in the body of residents of the above areas is not reduced).

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It is likely that a deficiency or excess of a number of microelements causes a deficiency in certain areas of the bone calcium, leads to disruption of collagen metabolism, deterioration of microcirculation, inhibition of regenerative (restorative) processes, changes in osteogenesis (bone formation) and early formation of immobile joints (synostoses). All these pathogenetic moments determine the development of degenerative changes in the tissues of the joints and a number of internal organs.

The second hypothesis is that the grain of the areas endemic for Urov disease is affected by sumatriptan pills fungus F. Sporotrichilla. It is assumed that the toxins of this fungus damage articular cartilage cells - chondrocytes, increase the formation of lipid peroxidation products toxic to cells. The third hypothesis states that Kashin-Beck disease is a hereditary pathology. Unfortunately, there is no direct evidence of this, but there is evidence that the children of people with it also fall ill several times more often than the children of healthy parents.

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In the bones of persons suffering from Kashin-Beck disease, a calcium deficiency and an excessive concentration of iron, manganese, silver and zinc were diagnosed, the level of phosphorus significantly exceeds the normal level both in their blood serum and in urine.

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In addition, there is a high risk of morbidity among close relatives. Probably, there is still some genetic predisposition to the appearance of imitrex deforming osteoarthritis, however, it does not guarantee the development of the disease in a certain person, but increases the likelihood of this in certain environmental conditions (living in an endemic area).

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Predisposing factors are considered rickets (vitamin D deficiency leads to poor absorption of calcium salts by the body), frequent hypothermia and intense physical activity, hard work of a person. The disease is based on a generalized process of skeletal degeneration.